Prior to further processing, each plasma pool is tested for the presence of viruses. The plasma is only used if it is non-reactive for the listed serological markers and for the virus genome (NAT). We test each plasma pool for the following serological markers: anti-HIV 1, anti-HIV 2, hepatitis B surface antigens, anti-HCV antibodies. In other words, we test each plasma pool for HIV antibodies, Hepatitis B antigens and Hepatitis C antibodies. We also test each plasma pool for the following virus genomes using NAT/PCR testing: Hepatitis A virus, Hepatitis B virus, Hepatitis C virus, HIV-1, B19 virus.

Serological Markers	Virus Genome (NAT) for DNA or RNA
HIV-1 antibodies	Hepatitis A Virus*
HIV-2 antibodies	Hepatitis B Virus
Hepatitis B antigens	Hepatitis C Virus (mandatory in EU)
Hepatitis C antibodies	HIV-1
	B19 Virus*

*Some plasma pools are not NAT-tested for Hepatitis A or B19 virus.